DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nine-amino-acid peptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) first isolated from rabbit brain in 1974. Research investigations have focused on its diverse neuromodulatory effects, including its role in promoting slow-wave (delta) sleep, modulating stress responses, and regulating endocrine function.
In research settings, DSIP has been studied for its interactions with multiple neurotransmitter systems, including GABA enhancement, NMDA receptor interaction, and endogenous opioid system modulation. Published studies have examined its effects on the hypothalamic-pituitary-adrenal axis, with investigations exploring its potential role in cortisol modulation and sleep efficiency without traditional sedative mechanisms.
Supplied as a lyophilized powder for reconstitution. Intended for research purposes only.
