Melanotan II is a cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH), originally developed at the University of Arizona. Research investigations have focused on its broad melanocortin receptor activity, binding to MC1R, MC3R, MC4R, and MC5R receptor subtypes. Studies have examined its stimulation of melanocytes to produce eumelanin through MC1R activation.
In research settings, Melanotan II has been studied for its effects on melanin production and pigmentation pathways. Published investigations have examined its pharmacokinetic profile, including its rapid absorption and relatively short half-life. Research has also explored its interactions with MC4R, which is involved in appetite regulation and energy homeostasis pathways, as well as its broader effects on melanocortin signaling systems.
Supplied as a lyophilized powder for reconstitution. Intended for research purposes only.
