AOD-9604 (Advanced Obesity Drug 9604) is a synthetic peptide corresponding to amino acids 176-191 of human growth hormone, with an added N-terminal tyrosine residue. Research investigations have focused on its selective action on fat metabolism, where it has been studied for stimulating lipolysis and inhibiting lipogenesis through beta-3 adrenergic receptor upregulation, without binding to the growth hormone receptor.
In preclinical models, AOD-9604 has been examined for its effects on body weight and fat oxidation. Unlike intact growth hormone, research has indicated that AOD-9604 does not increase IGF-1 levels, affect glucose metabolism, or promote insulin resistance. Additional investigations have explored its potential role in cartilage repair and joint health in animal models.
Supplied as a lyophilized powder for reconstitution. Intended for research purposes only.
